Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease.

A series of recent physiology studies span from rare disease mechanisms to space-based biomedical advances. Findings include a new mouse model for myofibrillar myopathy type 6 that identifies ...

Researchers Sumika Kato, Takeo Kubo, and Taro Fukazawa of the University of Tokyo have discovered that c1qtnf3, a secreting factor, namely a protein molecule that is secreted by a cell and influences ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically ...

In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday activities harder and increases the risk of falls, disability and early death.

Our hearts beat around 100,000 times a day—and do so throughout our entire lives. They draw the energy for this from the mitochondria. As the "powerhouses of the cells," mitochondria produce 95% of ...